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A list of all the posts and pages found on the site. For you robots out there is an XML version available for digesting as well.
Pages
About Me
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Posts
Future Blog Post
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Blog Post number 4
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Blog Post number 3
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Blog Post number 2
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Blog Post number 1
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portfolio
Modeling the Effect of Public Transit Accessibility on Diabetic Health Outcomes in Georgia
With DFU-related lower extremity amputations as the adverse outcome, we aimed to model geographic associations between amputations and measures of public transit usage and accessibility […] Across both the whole state of Georgia and within metro-Atlanta, accessibility of public transit and overall walkability of communities were significant predictors for observing fewer amputations, after adjusting for each ZCTA’s poverty level, personal vehicle availability, health insurance coverage, and primary care travel distance.
Natural Product-Drug Interaction (NaPDI) Research Data Repository
An open-source, publicly accessible data repository where researchers can access scientific results, raw data, and recommended approaches to optimally assess the clinical significance of pharmacokinetic natural product-drug interactions (PK-NPDIs).
My role in developing this site with a multidisciplinary team involved curating and designing its backend PostgreSQL database. I also conducted user testing interviews with pharmacology experts to identify UI-related preferences, and helped implement new use cases and information needs based on these interviews. Features I contributed included leveraging my SQL knowledge with Node.js implementation toward representing natural product experiment results through transforming principal component analysis (PCA) model results into 3-dimensional plots.
publications
Potentially Harmful Medication Use and Decline in Health-Related Quality of Life among Community-Dwelling Older Adults
Published in Drugs - Real World Outcomes, 2017
The aims of this study were to investigate an association between potentially harmful medication (PHM) use and change in health-related quality of life among community-dwelling older adults, and to compare the predictive capacity of PHM scales…
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Developing User Personas to Aid in the Design of a User-Centered Natural Product-Drug Interaction Information Resource for Researchers
Published in American Medical Informatics Association 2018 Annual Symposium, 2018
Pharmacokinetic interactions between natural products and conventional drugs can adversely impact patient outcomes. These complex interactions present unique challenges that require clear communication to researchers. We are creating a public information portal to facilitate researchers’ access to credible evidence about these interactions. As part of a user-centered design process, three types of intended researchers were surveyed: drug-drug interaction scientists, clinical pharmacists, and drug compendium editors…
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A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: from Chemical Characterization to Clinical Studies
Published in Drug Metabolism and Disposition, 2020
There are many gaps in scientific knowledge about the clinical significance of pharmacokinetic natural product-drug interactions (NPDIs) in which the NP is the precipitant and a conventional drug is the object. The National Center for Complimentary and Integrative Health created the Center of Excellence for NPDI Research (NaPDI Center) (www.napdi.org) to provide leadership and guidance on the study of pharmacokinetic NPDIs. A key contribution of the Center is the first user-friendly online repository that stores and links pharmacokinetic NPDI data across chemical characterization, metabolomics analyses, and pharmacokinetic in vitro and clinical experiments (repo.napdi.org)…
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Fall Risk-Increasing Drugs, Polypharmacy, and Falls Among Low-Income Community-Dwelling Older Adults
Published in Innovation In Aging, 2021
Medication exposure is a potential risk factor for falls and subsequent death and functional decline among older adults. However, controversy remains on the best way to assess medication exposure and which approach best predicts falls. The objective of the current study was to examine the association between different measures of medication exposure and falls risk among community-dwelling older adults.
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Designing and evaluating contextualized drug–drug interaction algorithms
Published in JAMIA Open, 2021
Alert fatigue is a common issue with off-the-shelf clinical decision support. Most warnings for drug–drug interactions (DDIs) are overridden or ignored, likely because they lack relevance to the patient’s clinical situation. Existing alerting systems for DDIs are often simplistic in nature or do not take the specific patient context into consideration, leading to overly sensitive alerts. The objective of this study is to develop, validate, and test DDI alert algorithms that take advantage of patient context available in electronic health records (EHRs) data.
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QTc Prolongation with the Use of Hydroxychloroquine and Concomitant Arrhythmogenic Medications: A Retrospective Study Using Electronic Health Records Data
Published in Drugs Real World Outcomes, 2022
The purpose of this study was to determine changes in the QTc interval in patients taking hydroxychloroquine with or without concomitant QT-prolonging medications, analyzing data from a large-scale retrospective health records database.
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Multimodal phenotyping and correlates of pain following hematopoietic cell transplant in children with sickle cell disease
Published in Pediatric Blood & Cancer, 2022
There is limited understanding of pain, psychological comorbidities associated with pain and HRQoL following transplantation for SCD. This study aimed to determine the feasibility and acceptability of collecting data on pain, patient-reported outcomes (PROs), HRQoL and experimental pain sensitivity using quantitative sensory testing (QST), and to compare these before and following HCT in patients with SCD. We hypothesized that there would be a decrease in pain burden following HCT and improvement in pain-associated psychological comorbidity.
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High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES)
Published in PAIN, 2024
In this study, we leveraged data previously collected in the landmark PiSCES study to examine the HICP phenotype in SCD. We proposed to compare the pain phenotype and outcomes between those with a HICP-like phenotype, hereafter referred to as the HICP group, with those who had CP but did not have HICP, hereafter referred to as the No-HICP group. We also examined the association between HRQoL outcomes and HICP status.
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talks
Talk 1 on Relevant Topic in Your Field
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Tutorial 1 on Relevant Topic in Your Field
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Talk 2 on Relevant Topic in Your Field
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Conference Proceeding talk 3 on Relevant Topic in Your Field
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teaching
Teaching experience 1
Undergraduate course, University 1, Department, 2014
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Teaching experience 2
Workshop, University 1, Department, 2015
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